INHIBITION OF DCLK1 KINASE REVERSES EPITHELIAL-MESENCHYMAL TRANSITION AND RESTORES T-CELL ACTIVITY IN PANCREATIC DUCTAL ADENOCARCINOMA

Inhibition of DCLK1 kinase reverses epithelial-mesenchymal transition and restores T-cell activity in pancreatic ductal adenocarcinoma

Immunotherapy has recently become a promising cancer therapy with extensive applications of immune checkpoint inhibitors Bush Shirts (ICIs).However, pancreatic ductal adenocarcinoma (PDAC) appears to be unresponsive to immunotherapy due to the immunosuppressive microenvironment.Recent studies showed that cancer stem cell marker DCLK1 promoted the i

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Effects on microhardness, tensile strength, deflection, and drop weight impact resistance with the addition of hybrid filler materials for enhancing GFRP composites

Abstract The work evaluated the usage of various filler materials, namely aluminium oxide (Al2O3), magnesium (Mg), and glass powder, in the bidirectional glass fibre reinforced polymer (GFRP) composites.The required samples were fabricated using the hand lay-up technique by varying the filler material proportions from 0%wt.to 7.5%wt., including ind

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Dataset of Smartphone-Based Finger Tapping Test

Abstract The finger tapping test (FTT) is a neuropsychological test that measures motor speed and coordination.It involves tapping a designated surface with a specific finger as quickly as possible for a certain duration.Touchscreen of smartphones has been used as interface to record the tap, what enables to extract information about the taps.The p

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Ultrasound elasticity imaging using Golay code

Ultrasound elasticity imaging is becoming a new diagnostic tool for clinicians to detect lesions or cancers in tissues.In this paper, Golay code is applied to elasticity imaging to improve its quality.Phase-zero algorithm is employed as the displacement estimator, and the amplitude NUTRITIONAL YEAST modulation correction location estimate method is

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